Gold nanoparticle based dot-blot immunoassay for sensitively detecting Alzheimer's disease related β-amyloid peptide.

نویسندگان

  • Chengke Wang
  • Dianjun Liu
  • Zhenxin Wang
چکیده

A simple, sensitive gold nanoparticle (GNP)-based dot-blot immunoassay has been developed for detecting Alzheimer's disease related β-amyloid peptide 1-42 (Aβ(1-42)) down to a 50 pg mL(-1) level in aqueous solution. Practical samples (cerebrospinal fluid (CSF), cell culturing mediums and cell lysates) have been used to demonstrate the ability of the assay.

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عنوان ژورنال:
  • Chemical communications

دوره 48 67  شماره 

صفحات  -

تاریخ انتشار 2012